In 2003, veteran AMS agent James Taylor and rookie Kate Green gather intelligence at the fifth basement floor of the AMS' European headquarters. James suspects that the events of the 2000 Goldman case have not ended. A sudden earthquake rocks the room, collapsing the basement walls and trapping the agents.
Several days later, while awaiting backup, James' PDA goes off; hordes of creatures appear on the security cameras. James and Kate arm themselves and escape. In a classified information room, they uncover a plot to fire nuclear missiles worldwide within 24 hours' time.