Eastern Mind is a point-and-click adventure game about a man named Rin who has lost his soul. A friend gives him an artificial soul that will last 49 days, with which he goes on a quest to the island of Tong Nou to recover his soul. The island takes the form of a human head and the player can enter its various orificies to access locations in the game. The player must die and be reincarnated as nine different creatures in order to complete nine unique missions. After dying, the outcome of Rin's transmigration is determined by the player's specific choice between three pairs of eyes, three noses, and three mouths. When every mission has been completed, the player is able to reach Central Mountain and recover Rin's soul.