Thanks to Meme Oshino, Koyomi Araragi, a high school student, is able to remain a human after coming across a female vampire. However, since the incident, Koyomi seems to meet girls who have an apparition-related issue. Hitagi Senjougahara doesn't weigh anything. Suruga Kanbaru’s left arm resembles that of a monkey’s. Nadeko Sengoku was afflicted by curses from her classmates. Mayoi Hachikuji, a young girl who cannot find her way home no matter how many times she tries. Koyomi, a Mr. Nice Guy, ends up helping each and every girl solve her problem with the help of Meme Oshino.